Buy JWH 200 Powder online
JWH 200 Powder: JWH-200 (1-pentyl-3-(1-naphthyl indole), also known as AM-678, is a cannabinoid receptor full agonist that works at both CB1 and CB2 cannabinoid receptors with little selectivity for CB2. It is used in synthetic cannabis products that are sold legally as “incense blends” in some countries because it has effects on animals that are comparable to those of tetrahydrocannabinol (THC), a cannabinoid that is undoubtedly present in hashish. Wistar rats that were given an ethanolic extract containing JWH-200 had their metabolism of the drug studied. After collecting urine for 24 hours, JWH-200’s metabolites were extracted using both liquid-liquid extraction and strong-segment extraction. To separate and understand the isolated chemicals, GC-MS was used. Only trace levels of JWH-200 and its N-dealkylated metabolite were found, with hydroxylated N-dealkylated metabolites serving as the main indicator. The found mass shift demonstrates that it is highly probable that hydroxylation occurs in both the molecule’s naphthalene and indole amounts. For JWH 018 product click here.
- The majority of human metabolism took place on the indole ring and pentyl side chain, and the hydroxylated metabolites were heavily conjugated with glucuronide, but overall, human metabolites were comparable.
- usage and purchase of JWH-2 hundred researches chemicals and at least one instance of JWH-200 dependence have been reported in the media. For eight months, the user took JWH-018 every day. The withdrawal symptoms were worse than those that were experienced due to hashish dependence. After treatment, JWH-200 has been shown to cause significant changes in CB1 receptor density. creating unexpectedly greater sensitivity to its effects than comparable cannabinoids
- JWH-200 Powder: JWH-2 hundred is a cannabinoid receptor agonist and analgesic drug belonging to the aminoalkylindole family. An aminoalkylindole known as JWH 200 functions as a ligand for the cannabinoid (CB) receptor. It has a strong affinity for the CB1 receptor (IC50 = 7.8–42 nM).
- An aminoalkylindole called JWH 200 functions as a ligand for the cannabinoid (CB) receptor. It binds to the CB1 receptor with a high degree of affinity (IC50 = 7.84 nM). 1,2. The results of JWH 200 are on par with or better than those of nine-THC or WIN 55,212 in the locomotor activity, tail-flick latency, hypothermia, and ring-immobility tests.
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